Plasma C24:0 ceramide impairs adipose tissue remodeling and promotes liver steatosis and glucose imbalance in offspring of rats

Plasma C24:0 ceramide impairs adipose tissue remodeling and promotes liver steatosis and glucose imbalance in offspring of rats

Fetal programming by exposure to high-energy diets increases the susceptibility to type 2 diabetes mellitus (T2DM2) in the offspring. Glucose imbalance during fetal programming might be associated to still unknown selective lipid species and their characterization might be beneficial for T2DM diagno...

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Main Authors: Alberto Camacho-Morales, Lilia G. Noriega, Adriana Sánchez-García, Ivan Torre-Villalvazo, Natalia Vázquez-Manjarrez, Roger Maldonado-Ruiz, Marcela Cárdenas-Tueme, Mariana Villegas-Romero, Itzayana Alamilla-Martínez, Humberto Rodriguez-Rocha, Aracely Garcia-Garcia, Juan Carlos Corona, Armando R. Tovar, Jennifer Saville, Maria Fuller, José Gerardo Gonzalez-Gonzalez, Ana María Rivas-Estilla
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
Subjects:
Diabetes
C24:0 ceramide
fetal programming
Adipose tissue remodeling
mitochondria
ER stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024152371
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