CanCellCap: robust cancer cell capture across tissue types on single-cell RNA-seq data by multi-domain learning

Abstract Background The advent of single-cell RNA sequencing (scRNA-seq) has provided unprecedented insights into cancer cellular diversity, enabling a comprehensive understanding of cancer at the single-cell level. However, identifying cancer cells remains challenging due to gene expression variabi...

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Bibliographic Details
Main Authors: Jiaxing Bai, Yichun Gao, Feng Zhou, Yushuang He, Chen Lin, Xiaobing Huang, Ying Wang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-025-02337-1
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