Functional Attributes of Synovial Fluid from Osteoarthritic Knee Exacerbate Cellular Inflammation and Metabolic Stress, and Fosters Monocyte to Macrophage Differentiation

Functional Attributes of Synovial Fluid from Osteoarthritic Knee Exacerbate Cellular Inflammation and Metabolic Stress, and Fosters Monocyte to Macrophage Differentiation

<b>Background:</b> Besides conventional norms that recognize synovial fluid (SF) as a joint lubricant, nutritional channel, and a diagnostic tool in knee osteoarthritis (kOA), based on the authors previous studies, this study aims to define functional role of SF in kOA. <b>Methods:...

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Bibliographic Details
Main Authors: Vanshika Srivastava, Abhay Harsulkar, Shama Aphale, Aare Märtson, Sulev Kõks, Priya Kulkarni, Shantanu Deshpande
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomedicines
Subjects:
DAMPs
mitochondrial membrane potential
osteoarthritis
synovial fluid
transcription-factors
Online Access:https://www.mdpi.com/2227-9059/13/4/878
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