Effect of the Nrf2/HO-1 pathway on aluminum-induced liver injury

Chronic exposure to aluminum (Al) can lead to the accumulation of Al in the liver, which negatively impacts liver structure and function. Oxidative stress is extensively identified as a key contributor to Al toxicity. The Nrf2/HO-1 pathway maintains cellular redox homeostasis and protects from oxida...

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Bibliographic Details
Main Authors: Xi Wei, Yueling Luo, Dongjie Yuan, Dong Li, Yixi Nong, Biaoliang Wu, Xiaojie Qin
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Ecotoxicology and Environmental Safety
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Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325008334
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