Primary Cilia Formation Mediated by Hsa_Circ_0005185/OTUB1/RAB8A Complex Inhibits Prostate Cancer Progression by Suppressing Hedgehog Signaling Pathway

Primary Cilia Formation Mediated by Hsa_Circ_0005185/OTUB1/RAB8A Complex Inhibits Prostate Cancer Progression by Suppressing Hedgehog Signaling Pathway

Abstract Prostate cancer (PCa) is one of the most common malignancies for male individuals globally. Androgen deprivation therapy (ADT) initially demonstrated significant efficacy in treating PCa; however, most cases of PCa eventually progress to castration‐resistant prostate cancer (CRPC), which be...

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Bibliographic Details
Main Authors: Aoyu Fan, Yunyan Zhang, Yunpeng Li, Wei Meng, Fan Wu, Wei Pan, Zhongliang Ma, Wei Chen
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
circular RNAs
deubiquitination
hedgehog signaling
primary cilia
prostate cancer
Otubain 1 (OTUB1)
Online Access:https://doi.org/10.1002/advs.202411675
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https://doi.org/10.1002/advs.202411675

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