In a Canine Model of Septic Shock, Cardiomyopathy Occurs Independent of Catecholamine Surges and Cardiac Microvascular Ischemia

In a Canine Model of Septic Shock, Cardiomyopathy Occurs Independent of Catecholamine Surges and Cardiac Microvascular Ischemia

Background High levels of catecholamines are cardiotoxic and associated with stress‐induced cardiomyopathies. Using a septic shock model that reproduces the reversible cardiomyopathy seen over 10 days associated with human septic shock, we investigated the effects of catecholamines on microcirculato...

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Bibliographic Details
Main Authors: Verity J. Ford, Willard N. Applefeld, Jeffrey Wang, Junfeng Sun, Steven B. Solomon, Harvey G. Klein, Jing Feng, Juan Lertora, Parizad Parizi‐Torabi, Robert L. Danner, Michael A. Solomon, Marcus Y. Chen, Charles Natanson
Format: Article
Language:English
Published: Wiley 2024-08-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
catecholamine levels
microcirculatory perfusion
septic cardiomyopathy
stress‐induced cardiomyopathy
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.034027
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https://www.ahajournals.org/doi/10.1161/JAHA.123.034027

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