Protocol for adeno-associated virus-mediated gene delivery to accelerate pancreatic carcinogenesis in mice

Summary: Introducing additional genetic modifications or environmental stimuli accelerates early pancreatic carcinogenesis in the p48Cre/+; LSL-KrasG12D/+ (KC) mouse model. Here, we present a protocol employing adeno-associated virus (AAV)-mediated gene delivery specifically in the pancreas to facil...

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Bibliographic Details
Main Authors: Hongzhen Li, Zhao Shi, Shanshan Shen, Bo Kong
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:STAR Protocols
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666166725003132
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