NAT10 promotes liver lipogenesis in mouse through N4-acetylcytidine modification of Srebf1 and Scap mRNA

Abstract Background Metabolic dysfunction associated steatotic liver disease (MASLD), closely linked to excessive lipogenesis, induces chronic liver disease. MASLD often cause other metabolic diseases, such as cardiovascular disease, diabetes and obesity. However, the mechanism of N-acetyltransferas...

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Bibliographic Details
Main Authors: Zhouqi Wang, Xinxing Wan, Md Asaduzzaman Khan, Lin Peng, Xiaoying Sun, Xuan Yi, Ke Chen
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Lipids in Health and Disease
Subjects:
Online Access:https://doi.org/10.1186/s12944-024-02360-1
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