Sentrin/SUMO specific proteases as novel tissue-selective modulators of vitamin D receptor-mediated signaling.

Sentrin/SUMO specific proteases as novel tissue-selective modulators of vitamin D receptor-mediated signaling.

Vitamin D receptor (VDR) is a substrate for modification with small ubiquitin-like modifier (SUMO). To further assess the role of reversible SUMOylation within the vitamin D hormonal response, we evaluated the effects of sentrin/SUMO-specific proteases (SENPs) that can function to remove small ubiqu...

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Bibliographic Details
Main Authors: Wai-Ping Lee, Sarita Jena, Declan Doherty, Jaganathan Ventakesh, Joachim Schimdt, Julie Furmick, Tim Widener, Jana Lemau, Peter W Jurutka, Paul D Thompson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089506&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089506&type=printable

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