Endothelial cells expressing CPE and vWF are involved in the Immunopathogenesis of primary biliary cholangitis

Abstract Primary biliary cholangitis (PBC) is an immune-mediated, non-suppurative cholestatic liver disease. Liver sinusoidal endothelial cells (LSECs) play a pivotal role in maintaining hepatic immune tolerance. Emerging research indicates that under certain stimuli, LSECs can transition from a tol...

Full description

Saved in:
Bibliographic Details
Main Authors: Lin-Xiang Huang, Zi-Xuan Qiu, Xiao-Xiao Wang, Zi-Long Wang, Bo Feng
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-07311-z
Tags: Add Tag
No Tags, Be the first to tag this record!