Evaluating Bioassays for the Determination of Simvastatin’s Osteogenic Activity: A Systematic Review

Evaluating Bioassays for the Determination of Simvastatin’s Osteogenic Activity: A Systematic Review

Objective: Osteogenic differentiation is a complex process, and its analysis requires several biomarkers. Allied with this, there are no standardized bioassays to monitor the activity of simvastatin in osteogenesis in vitro. Therefore, identifying the most efficient and sensitive bioassays may enhan...

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Bibliographic Details
Main Authors: Lara Steiner Back, Isabella Schönhofen Manso, Mariane Beatriz Sordi, Gabriel Leonardo Magrin, Águedo Aragonês, Ricardo de Souza Magini, Reinhard Gruber, Ariadne Cristiane Cabral Cruz
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Journal of Functional Biomaterials
Subjects:
simvastatin
mesenchymal stromal cell
osteogenesis
osteoblast
mineralization
Online Access:https://www.mdpi.com/2079-4983/16/2/61
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