Facilitating DNAzyme transport across the blood-brain barrier with nanoliposome technology
Abstract Recently, oligonucleotide post-transcriptional gene silencing, antisense oligonucleotides, small interfering RNA, ribozymes, and Deoxyribozymes (DNAzymes) have been used to tackle neurodegenerative diseases such as Alzheimer’s and polyglutamine diseases like Huntington’s disease. However, t...
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| Main Authors: | Mohammad Javad Hoseinifar, Faranak Aghaz, Zahra Asadi, Peyman Asadi, Seyed Ershad Nedaei, Elham Arkan, Ali Pourmotabbed, Gholamreza Bahrami, Tayebeh Pourmotabbed |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-04433-2 |
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