Off-label therapeutic potential of topical roflumilast in dermatology: A narrative reviewCapsule Summary
Topical roflumilast, a potent phosphodiesterase-4 inhibitor, was recently approved for the treatment of plaque psoriasis, seborrheic dermatitis, and atopic dermatitis. By reducing cyclic adenosine monophosphate degradation, roflumilast downregulates proinflammatory cytokines implicated in a variety...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-12-01
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| Series: | JAAD Reviews |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950198925000741 |
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