Constructing multilayer PPI networks based on homologous proteins and integrating multiple PageRank to identify essential proteins
Abstract Background Predicting and studying essential proteins not only helps to understand the fundamental requirements for cell survival and growth regulation mechanisms but also deepens our understanding of disease mechanisms and drives drug development. Existing methods for identifying essential...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
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| Series: | BMC Bioinformatics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12859-025-06093-5 |
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