Foot-and-Mouth Disease Vaccines by Design; Production of Capsid-Modified Foot-and-Mouth Disease Viruses with Improved Cell Culture Growth

Foot-and-Mouth Disease Vaccines by Design; Production of Capsid-Modified Foot-and-Mouth Disease Viruses with Improved Cell Culture Growth

Background/Objectives: Vaccination is important for controlling foot-and-mouth disease (FMD) in endemic regions and to lessen the effects of outbreaks in FMD-free countries. The adaptation of FMD virus to BHK cells is a necessary but time-consuming and costly step in vaccine production and can prove...

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Bibliographic Details
Main Authors: Stephen Berryman, Femke Feenstra, Amin Asfor, Jose Coco-Martin, Terry Jackson, Tobias J. Tuthill
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Vaccines
Subjects:
FMDV
vaccine
tissue culture adaptation
reverse genetics
heparan sulfate
Online Access:https://www.mdpi.com/2076-393X/13/3/281
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