Integrated single-cell sequencing for the development of a GJA4-based precision immuno-prognostic model in melanoma

Integrated single-cell sequencing for the development of a GJA4-based precision immuno-prognostic model in melanoma

Methods: We conducted an analysis of RNA-seq and microarray data obtained from the TCGA and GEO databases, alongside single-cell RNA sequencing (scRNA-seq) data from glioma patients within the GEO repository. This comprehensive investigation, augmented by experimental studies, concentrated on explor...

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Bibliographic Details
Main Authors: Yantao Ding, Si Xie, Wenyang Nie, Yun Bai, Tianyu Yao, Yixiao Wang, Jiajie Chen, Bo Liang, Yi Zhou, Hui Cheng, Zaixing Wang, Shengxiu Liu
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Translational Oncology
Subjects:
Melanoma
GJA4
Diagnosis
Prognosis
Tumor-associated endothelial cells
Personalized therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325001810
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