Immune cell aberrations in Systemic Lupus Erythematosus: navigating the targeted therapies toward precision management

Abstract Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by multilayered dysregulation of immune cell homeostasis, spanning B cell effector dysfunction, T follicular helper (Tfh) cell hyperactivity, and plasmacytoid dendritic cell (pDC) tolerance breakdown. Advances...

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Bibliographic Details
Main Authors: YuXian Wu, Wangzheqi Zhang, Yan Liao, Ting Sun, Yang Liu, Yaoyang Liu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:https://doi.org/10.1186/s11658-025-00749-z
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