Impact of Donor-Specific anti-HLA antibodies and donor KIR characteristics in haploidentical HSCT for beta-Thalassemia

Impact of Donor-Specific anti-HLA antibodies and donor KIR characteristics in haploidentical HSCT for beta-Thalassemia

In the present study we investigated the role of donor specific HLA antibodies (DSA) and donor KIR repertoire characteristics in a group of 18 patients affected by haemoglobinopathies who underwent haploidentical T cell depleted transplantation. Among these patients, 8 rejected the transplant while...

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Bibliographic Details
Main Authors: Marco Andreani, Manuela Testi, Pietro Sodani, Maria Troiano, Andrea Di Luzio, Giuseppe Testa, Michela Falco, Elvira Poggi, Javid Gaziev, Antonina Piazza
Format: Article
Language:English
Published: PAGEPress Publications 2017-03-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Haploidentical HSCT, KIR receptors, anti-HLA antibodies
Online Access:http://www.mjhid.org/index.php/mjhid/article/view/2843
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http://www.mjhid.org/index.php/mjhid/article/view/2843

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