Annotation of genomics data using bidirectional hidden Markov models unveils variations in Pol II transcription cycle

Abstract DNA replication, transcription and repair involve the recruitment of protein complexes that change their composition as they progress along the genome in a directed or strand‐specific manner. Chromatin immunoprecipitation in conjunction with hidden Markov models (HMMs) has been instrumental...

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Bibliographic Details
Main Authors: Benedikt Zacher, Michael Lidschreiber, Patrick Cramer, Julien Gagneur, Achim Tresch
Format: Article
Language:English
Published: Springer Nature 2014-12-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.15252/msb.20145654
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