Identification of prognostic biomarker of non-small cell lung cancer based on mitochondrial permeability transition-driven necrosis-related genes and determination of anti-tumor effect of ARL14
Abstract Background Mitochondrial permeability transition (MPT)-driven necrosis (MPTDN) is a non-apoptotic mode of cell death triggered by oxidative stress and cytosolic Ca2+ overload. Recent evidence suggests that activation of MPTND can effectively induce cancer cell death and may represent a nove...
Saved in:
| Main Authors: | Zhifei Ma, Wen Chen, Aiping Zhang, Xiaokang Shen, Lin Zheng |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-02-01
|
| Series: | Hereditas |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41065-025-00379-7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Targeting FCRLA to induce necrosis in lung adenocarcinoma: a novel strategy for prognosis and therapy via MPT-Driven pathways
by: Xiaoli Sun, et al.
Published: (2025-08-01) -
Small GTPase ARL4C Associated with Various Cancers Affects Microtubule Nucleation
by: Evgeniia Ulas, et al.
Published: (2024-12-01) -
Mitochondrial functional impairment in ARL3‐mutation related rod‐cone dystrophy
by: Xiaoli Zhang, et al.
Published: (2024-11-01) -
ARL8B regulates lysosomal function and predicts poor prognosis in hepatocellular carcinoma
by: Liyan Wu, et al.
Published: (2025-04-01) -
Identification and multi-dimensional validation of mitochondrial permeability transition-driven necrosis-related model to assess the prognosis and immunotherapy value in breast cancer
by: Jinsong Liu, et al.
Published: (2025-02-01)