Identification of prognostic biomarker of non-small cell lung cancer based on mitochondrial permeability transition-driven necrosis-related genes and determination of anti-tumor effect of ARL14

Abstract Background Mitochondrial permeability transition (MPT)-driven necrosis (MPTDN) is a non-apoptotic mode of cell death triggered by oxidative stress and cytosolic Ca2+ overload. Recent evidence suggests that activation of MPTND can effectively induce cancer cell death and may represent a nove...

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Bibliographic Details
Main Authors: Zhifei Ma, Wen Chen, Aiping Zhang, Xiaokang Shen, Lin Zheng
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Hereditas
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Online Access:https://doi.org/10.1186/s41065-025-00379-7
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