Anti-HBs Positivity Related to Past HBV Infection and Vaccination in Older Adults in Polish Population—Cohort-Based Study
Background: In Poland, a national hepatitis B (HBV) immunization program was introduced for neonates in 1996, and between 2000 and 2011, those born from 1986 to 1995 were vaccinated. Little is known about vaccination rates among adults born before 1986. This study aimed to determine the frequency of...
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MDPI AG
2024-12-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/13/1/18 |
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| author | Katarzyna Zięba Kacper Jagiełło Joanna Musialik Łukasz Wierucki Adam Hajduk Małgorzata Mossakowska Jerzy Chudek |
| author_facet | Katarzyna Zięba Kacper Jagiełło Joanna Musialik Łukasz Wierucki Adam Hajduk Małgorzata Mossakowska Jerzy Chudek |
| author_sort | Katarzyna Zięba |
| collection | DOAJ |
| description | Background: In Poland, a national hepatitis B (HBV) immunization program was introduced for neonates in 1996, and between 2000 and 2011, those born from 1986 to 1995 were vaccinated. Little is known about vaccination rates among adults born before 1986. This study aimed to determine the frequency of anti-HBs seropositivity rates related to vaccination and past HBV infection in older Poles. Methods: The HBV serological status was analyzed in 5781 (96.6%) of the PolSenior2 population-based cohort (60+) by assessing serum seropositivity for HBs antigen, anti-HBs, and anti-HBc antibodies. The survey was performed in 2018–2019 and included medical and socio-economic questionnaires, anthropometric measurements, and comprehensive geriatric assessment. Results: Serological status implying past hepatitis B and serological profile consistent with anti-HBV vaccination corresponded to 15.2% (95% CI: 13.4–17.0) and 25.2% (95% CI: 23.4–27.0) prevalences, respectively. Female gender, living in a town or city, having better education, and suffering from coronary artery disease, or depression independently increased the rate of past hepatitis B. On the other hand, being ‘white collar’ and self-reliant, having the ability to use the Internet, and past surgical procedures in the last 5-year period were factors associated with a higher vaccination rate. Conclusions: More than 15% of older adults in Poland present serological profiles suggesting past hepatitis B, and one-fourth anti-HBV vaccination. Being functionally independent, ‘white collar’, using the Internet, and having past surgical procedures are factors associated with a higher chance of being vaccinated. Nevertheless, a large group of older adults should be prophylactically vaccinated due to increased exposure to medical procedures. |
| format | Article |
| id | doaj-art-a467adcc5d7f4b24904fe38b92f6e9a2 |
| institution | Kabale University |
| issn | 2076-393X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj-art-a467adcc5d7f4b24904fe38b92f6e9a22025-01-24T13:51:40ZengMDPI AGVaccines2076-393X2024-12-011311810.3390/vaccines13010018Anti-HBs Positivity Related to Past HBV Infection and Vaccination in Older Adults in Polish Population—Cohort-Based StudyKatarzyna Zięba0Kacper Jagiełło1Joanna Musialik2Łukasz Wierucki3Adam Hajduk4Małgorzata Mossakowska5Jerzy Chudek6Department of Internal Medicine and Oncological Chemotherapy, Medical University of Silesia in Katowice, 40-029 Katowice, PolandDepartment of Preventive Medicine and Education, Medical University of Gdańsk, 80-211 Gdańsk, PolandDepartment of Nephrology, Transplantology and Internal Medicine, Medical University of Silesia in Katowice, 40-055 40-027 Katowice, PolandDepartment of Preventive Medicine and Education, Medical University of Gdańsk, 80-211 Gdańsk, PolandDepartment of Rheumatology, Clinical Immunology, Geriatrics and Internal Medicine, Medical University of Gdańsk, 80-214 Gdańsk, PolandStudy on Ageing and Longevity, International Institute of Molecular and Cell Biology, 02-109 Warsaw, PolandDepartment of Internal Medicine and Oncological Chemotherapy, Medical University of Silesia in Katowice, 40-029 Katowice, PolandBackground: In Poland, a national hepatitis B (HBV) immunization program was introduced for neonates in 1996, and between 2000 and 2011, those born from 1986 to 1995 were vaccinated. Little is known about vaccination rates among adults born before 1986. This study aimed to determine the frequency of anti-HBs seropositivity rates related to vaccination and past HBV infection in older Poles. Methods: The HBV serological status was analyzed in 5781 (96.6%) of the PolSenior2 population-based cohort (60+) by assessing serum seropositivity for HBs antigen, anti-HBs, and anti-HBc antibodies. The survey was performed in 2018–2019 and included medical and socio-economic questionnaires, anthropometric measurements, and comprehensive geriatric assessment. Results: Serological status implying past hepatitis B and serological profile consistent with anti-HBV vaccination corresponded to 15.2% (95% CI: 13.4–17.0) and 25.2% (95% CI: 23.4–27.0) prevalences, respectively. Female gender, living in a town or city, having better education, and suffering from coronary artery disease, or depression independently increased the rate of past hepatitis B. On the other hand, being ‘white collar’ and self-reliant, having the ability to use the Internet, and past surgical procedures in the last 5-year period were factors associated with a higher vaccination rate. Conclusions: More than 15% of older adults in Poland present serological profiles suggesting past hepatitis B, and one-fourth anti-HBV vaccination. Being functionally independent, ‘white collar’, using the Internet, and having past surgical procedures are factors associated with a higher chance of being vaccinated. Nevertheless, a large group of older adults should be prophylactically vaccinated due to increased exposure to medical procedures.https://www.mdpi.com/2076-393X/13/1/18hepatitis BvaccinationHBVolder adults |
| spellingShingle | Katarzyna Zięba Kacper Jagiełło Joanna Musialik Łukasz Wierucki Adam Hajduk Małgorzata Mossakowska Jerzy Chudek Anti-HBs Positivity Related to Past HBV Infection and Vaccination in Older Adults in Polish Population—Cohort-Based Study Vaccines hepatitis B vaccination HBV older adults |
| title | Anti-HBs Positivity Related to Past HBV Infection and Vaccination in Older Adults in Polish Population—Cohort-Based Study |
| title_full | Anti-HBs Positivity Related to Past HBV Infection and Vaccination in Older Adults in Polish Population—Cohort-Based Study |
| title_fullStr | Anti-HBs Positivity Related to Past HBV Infection and Vaccination in Older Adults in Polish Population—Cohort-Based Study |
| title_full_unstemmed | Anti-HBs Positivity Related to Past HBV Infection and Vaccination in Older Adults in Polish Population—Cohort-Based Study |
| title_short | Anti-HBs Positivity Related to Past HBV Infection and Vaccination in Older Adults in Polish Population—Cohort-Based Study |
| title_sort | anti hbs positivity related to past hbv infection and vaccination in older adults in polish population cohort based study |
| topic | hepatitis B vaccination HBV older adults |
| url | https://www.mdpi.com/2076-393X/13/1/18 |
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