MicroRNA-122 overexpression suppresses the colon cancer cell proliferation by downregulating the astrocyte elevated gene-1/metadherin oncoprotein

MicroRNA-122 overexpression suppresses the colon cancer cell proliferation by downregulating the astrocyte elevated gene-1/metadherin oncoprotein

Background MicroRNAs (miRNAs) are small non-coding RNAs that regulate essential cellular functions, such as cell adhesion, proliferation, migration, invasion, and programmed cell death, and therefore, alterations in miRNAs can contribute to carcinogenesis. Previous studies have shown that miRNA-122...

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Main Authors: Sarubala Malayaperumal, Sushmitha Sriramulu, Ganesan Jothimani, Antara Banerjee, Hong Zhang, Shabana Thabassum Mohammed Rafi, Ilangovan Ramachandran, Rajesh Kanna NR, Xiao-Feng Sun, Surajit Pathak
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Annals of Medicine
Subjects:
miR-122
colon cancer
inflammatory cytokines
apoptosis
TCGA-COAD
AEG-1/MTDH
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2025.2478311
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https://www.tandfonline.com/doi/10.1080/07853890.2025.2478311

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