Chromatin remodelling factor BAF155 protects hepatitis B virus X protein (HBx) from ubiquitin-independent proteasomal degradation

Chromatin remodelling factor BAF155 protects hepatitis B virus X protein (HBx) from ubiquitin-independent proteasomal degradation

HBx is a short-lived protein whose rapid turnover is mainly regulated by ubiquitin-dependent proteasomal degradation pathways. Our prior work identified BAF155 to be one of the HBx binding partners. Since BAF155 has been shown to stabilize other members of the SWI/SNF chromatin remodelling complex b...

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Bibliographic Details
Main Authors: Huijing Chen, Yi Zhang, Shuangshuang Ye, Qiong Wu, Youfen Lin, Kaiqin Sheng, Wannan Chen, Xinjian Lin, Xu Lin
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Emerging Microbes and Infections
Subjects:
Hepatitis B virus X protein
chromatin remodelling factor BAF155
ubiquitin-dependent and -independent proteasomal degradation
proteasomal subunit PSMA7
hpatocellular carcinoma
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2019.1666661
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https://www.tandfonline.com/doi/10.1080/22221751.2019.1666661

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