Changes in Spo0A~P pulsing frequency control biofilm matrix deactivation.

Under starvation conditions, B. subtilis survives by differentiating into one of two cell types: biofilm matrix-producing cells or sporulating cells. These two cell-differentiation pathways are activated by the same phosphorylated transcription factor - Spo0A~P. Despite sharing the activation mechan...

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Bibliographic Details
Main Authors: Cristina S D Palma, Daniel J Haller, Jeffrey J Tabor, Oleg A Igoshin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1013263
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