2-Dodecyl-6-methoxycyclohexa-2,5-dien-1,4-dione alleviates liver fibrosis and improves intestinal flora and bile acid metabolism
BackgroundThe bioactive compound 2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione (DMDD), derived from the horn root of star fruit, exhibits therapeutic promise through its modulation of the TGF-β1 pathway and regulation of bile acids.MethodsIn this study, a liver fibrosis model was established in K...
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| Main Authors: | Yongfei He, Thi Thai Hoa Pham, Junming Xu, Shengjie Hong, Jicai Wang, Hang Zhai, Qiang Tao, Ruixi Li, Guangquan Zhang, Xianjie Shi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1581138/full |
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