LPM682000012, a Synthetic Neuroactive Steroid That Ameliorates Epileptic Seizures by Downregulating the <i>Serpina3n</i>/NF-κB Signaling Pathway

LPM682000012, a Synthetic Neuroactive Steroid That Ameliorates Epileptic Seizures by Downregulating the <i>Serpina3n</i>/NF-κB Signaling Pathway

Epilepsy is characterized by abnormal neuronal firing in the brain. Several therapeutic strategies exist for epilepsy; however, several patients remain poorly treated. Therefore, the development of effective treatments remains a high priority in the field. Neuroactive steroids can potentiate extra-s...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaofan Zhang, Shengmin Ji, Yue Yang, Xiaohui Sun, Hui Wang, Yifan Yang, Xuan Deng, Yunjie Wang, Chunmei Li, Jingwei Tian
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
Subjects:
epilepsy
PAM
GABA<sub>A</sub> receptor
NASs
<i>Serpina3n</i>
NF-κB
Online Access:https://www.mdpi.com/1420-3049/29/22/5286
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1420-3049/29/22/5286

Similar Items