Strategies for CRISPR-based knock-ins in primary human B cells and lymphoma cell lines

Since its advent about ten years ago, the CRISPR-Cas9 system has been frequently used in biomedical applications. It has advanced various fields, and CRISPR-Cas9-based therapeutics have shown promising results in the treatment of specific hematological diseases. Furthermore, CRISPR gene editing tech...

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Bibliographic Details
Main Authors: Sophie Lund, Chun Gong, Xin Yu, Louis M. Staudt, Daniel J. Hodson, Sebastian Scheich
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1589729/full
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