An intracellular bacterial pathogen triggers RIG-I/MDA5-dependent necroptosis

RIG-I and MDA5 are members of RIG-I-like receptors (RLRs) that detect viral RNA within the cytoplasm and subsequently initiate antiviral immune responses. Necroptosis is a form of programmed cell death (PCD) executed by mixed lineage kinase domain-like (MLKL), which, upon phosphorylation by receptor...

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Bibliographic Details
Main Authors: Hang Xu, Huili Li, Boguang Sun, Li Sun
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Current Research in Microbial Sciences
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666517424001019
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