Neuroprotection by Mitochondrial NAD Against Glutamate-Induced Excitotoxicity

Neuroprotection by Mitochondrial NAD Against Glutamate-Induced Excitotoxicity

Excitotoxicity is a pathological process that occurs in many neurological diseases, such as stroke or epilepsy, and is characterized by the extracellular accumulation of high concentrations of glutamate or other excitatory amino acids (EAAs). Nicotinamide adenine dinucleotide (NAD) depletion is an e...

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Bibliographic Details
Main Authors: Bruna S. Paiva, Diogo Neves, Diogo Tomé, Filipa J. Costa, Inês C. Bruno, Diogo Trigo, Raquel M. Silva, Ramiro D. Almeida
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Cells
Subjects:
excitotoxicity
mitochondria
NAD metabolism
glutamate
Online Access:https://www.mdpi.com/2073-4409/14/8/582
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