Unveiling the Anticancer Potential of a New Ciprofloxacin-Chalcone Hybrid as an Inhibitor of Topoisomerases I & II and Apoptotic Inducer

Unveiling the Anticancer Potential of a New Ciprofloxacin-Chalcone Hybrid as an Inhibitor of Topoisomerases I & II and Apoptotic Inducer

The current study has yielded promising results in the evaluation of a new ciprofloxacin-chalcone hybrid (CP derivative) for its anticancer activity as potential Topoisomerases (Topo) I and II inhibitors. The in vitro results showed that the CP derivative significantly suppressed the growth of HCT-1...

Full description

Saved in:
Bibliographic Details
Main Authors: Doaa Mohamed Elroby Ali, Hossameldin A. Aziz, Stefan Bräse, Areej Al Bahir, Abdullah Alkhammash, Gamal El-Din A. Abuo-Rahma, Ali M. Elshamsy, Hamada Hashem, Walid M. Abdelmagid
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
Subjects:
ciprofloxacin
anti-proliferative
topoisomerases I & II inhibitor
apoptotic inducer
molecular docking
Online Access:https://www.mdpi.com/1420-3049/29/22/5382
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1420-3049/29/22/5382

Similar Items