Expression signatures with specificity for type I and II IFN response and relevance for autoimmune diseases and cancer

Abstract Background Aberrant interferon signaling is a key element of various diseases, but resolving gene expression signatures that stem from different types of IFNs in tissue samples is still a challenge. Most published IFN signatures comprise genes that are activated by different IFNs: they cann...

Full description

Saved in:
Bibliographic Details
Main Authors: Bogac Aybey, Benedikt Brors, Eike Staub
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06628-7
Tags: Add Tag
No Tags, Be the first to tag this record!