The development of a high-plex spatial proteomic methodology for the characterisation of the head and neck tumour microenvironment

The development of a high-plex spatial proteomic methodology for the characterisation of the head and neck tumour microenvironment

Abstract Head and neck squamous cell carcinoma (HNSCC) is a debilitating disease that accounts for an estimated 890,000 new cases per year. Despite advancements in chemotherapy, radiotherapy, surgery and immunotherapy, the prognosis of HNSCC has remained relatively unchanged for more than a decade....

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Main Authors: Chin Wee Tan, Naomi Berrell, Meg L. Donovan, James Monkman, Clara Lawler, Habib Sadeghirad, Vahid Yaghoubi Naei, Jinjin Chen, Alyssa Rossenbloom, Shilah Bonnett, Mark Conner, Brian Filanoski, Christine Kang, Joseph M. Beechem, John F. Fraser, Catherine Barnett, Rahul Ladwa, Brett G. M. Hughes, Arutha Kulasinghe
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-00963-0
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https://doi.org/10.1038/s41698-025-00963-0

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