PCDH17 induces colorectal cancer metastasis by destroying the vascular endothelial barrier
Abstract Compromised vascular integrity facilitates the cancer cells extravasation and metastasis. However, the mechanisms leading to a disruption in vascular integrity in colorectal cancer (CRC) remain unclear. In this study, PCDH17 expression was higher in the vascular endothelial cells of colon c...
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| Main Authors: | Fengyun Dong, Pinghui Zhou, Feifei Kong, Sijie Cao, Xiaozao Pan, Shujing Cai, Xinke Chen, Sen Wang, Na Li, Baoyu He, Rou Zhao, Bin Zhang, Qingli Bie |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-01-01
|
| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-025-07355-z |
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