PCDH17 induces colorectal cancer metastasis by destroying the vascular endothelial barrier

Abstract Compromised vascular integrity facilitates the cancer cells extravasation and metastasis. However, the mechanisms leading to a disruption in vascular integrity in colorectal cancer (CRC) remain unclear. In this study, PCDH17 expression was higher in the vascular endothelial cells of colon c...

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Bibliographic Details
Main Authors: Fengyun Dong, Pinghui Zhou, Feifei Kong, Sijie Cao, Xiaozao Pan, Shujing Cai, Xinke Chen, Sen Wang, Na Li, Baoyu He, Rou Zhao, Bin Zhang, Qingli Bie
Format: Article
Language:English
Published: Nature Publishing Group 2025-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07355-z
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