Efficacy and safety of esketamine in preventing perioperative neurocognitive disorders: a meta-analysis of randomized controlled studies

Efficacy and safety of esketamine in preventing perioperative neurocognitive disorders: a meta-analysis of randomized controlled studies

Abstract Background Perioperative neurocognitive disorders (POND) are common in older adults and are associated with adverse outcomes. This meta-analysis aimed to evaluate the efficacy and safety of esketamine for the prophylaxis of POND. Methods Electronic databases were comprehensively searched fr...

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Main Authors: Kuo-Chuan Hung, Chia-Li Kao, Chun-Ning Ho, Jheng-Yan Wu, Ying-Jen Chang, Chien-Ming Lin, I-Wen Chen
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Systematic Reviews
Subjects:
Perioperative neurocognitive disorders
Esketamine
Postoperative
Inflammatory markers
Cognitive function
Online Access:https://doi.org/10.1186/s13643-025-02807-1
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https://doi.org/10.1186/s13643-025-02807-1

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