Bavachin ameliorates cisplatin-induced nephrotoxicity by enhancing mitochondrial β-oxidation and lipid metabolism through MFN2

Abstract Background Cisplatin-induced nephrotoxicity is a critical adverse reaction that restricts the clinical utilization of cisplatin. Alterations in fatty acid metabolism have been associated with the pathogenesis of cisplatin-induced nephrotoxicity, yet the precise mechanisms remain unclear. Ba...

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Bibliographic Details
Main Authors: Shilu Luo, Ming Yang, Na Jiang, Chenrui Li, Yan Liu, Lin Sun
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Molecular Medicine
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Online Access:https://doi.org/10.1186/s10020-025-01283-6
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