Humoral vaccine responses following Chimeric Antigen Receptor T-cell therapy for hematological malignancies

Humoral vaccine responses following Chimeric Antigen Receptor T-cell therapy for hematological malignancies

Abstract This single-center, retrospective study analyzed vaccine responses in patients who received post-Chimeric Antigen Receptor (CAR) T-cell therapy vaccination between 2018 and 2024. Vaccinations were administered according to EBMT/CIBMTR recommendations and pathogen-specific IgG responses to 1...

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Main Authors: Sigrun Einarsdottir, Stephanie Lobaugh, Danny Luan, Marina Gomez-Llobell, Padmapriya Subramanian, Sean Devlin, David Chung, Parastoo B. Dahi, Lorenzo Falchi, Sergio Giralt, Heather Landau, Alexander M. Lesokhin, Richard Lin, Jennifer Lue, Sham Mailankody, M. Lia Palomba, Jae H. Park, Gilles Salles, Michael Scordo, Silvia Escribano-Serrat, Jaime Sanz, Kai Rejeski, Roni Shouval, Saad Usmani, Miguel-Angel Perales, Gunjan Shah, Zainab Shahid
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-025-01321-w
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https://doi.org/10.1038/s41408-025-01321-w

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