Clinical characterization and genetic analysis of transient abnormal myelopoiesis without the down syndrome phenotype

Background: Transient abnormal myelopoiesis (TAM) is a congenital leukemia specific to neonates with Down syndrome (DS) or trisomy 21. However, rare cases of TAM can also occur with acquired trisomy 21 mutations or mosaic trisomy 21, leading to potential misdiagnosis due to the absence of the DS phe...

Full description

Saved in:
Bibliographic Details
Main Authors: Junpeng Cai, Xiaomin Zhou, Yu Zhou, Guanghuan Pi
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Molecular Genetics and Metabolism Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214426924001307
Tags: Add Tag
No Tags, Be the first to tag this record!