Mutation of the histone demethylase Gasc1 causes ASD-like symptoms in mice

Mutation of the histone demethylase Gasc1 causes ASD-like symptoms in mice

Abstract Background Genomic analyses of psychiatric disorders, including autism spectrum disorder (ASD), have revealed many susceptibility genes, suggesting that such disorders may be caused by multiple factors. In this sense, it has long been a question whether there is an abnormal genetic status t...

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Main Authors: Tetsushi Kagawa, Yuhei Yamaguchi, Yasuhiro Kokubu, Genki Sudo, Aoi Ebisawa, Satoko Hattori, Keizo Takao, Kohtarou Konno, Naomi Nakagata, Takafumi Inoue, Masahiko Watanabe, Johji Inazawa, Tsuyoshi Miyakawa, Tetsuya Taga
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Inflammation and Regeneration
Subjects:
Autism spectrum disorders
Hyperactivity
Epigenome
Histone methylation
GASC1
KDM4 C
Online Access:https://doi.org/10.1186/s41232-025-00374-5
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https://doi.org/10.1186/s41232-025-00374-5

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