Ad‐E6/7‐HR vaccine improves the prophylactic and therapeutic efficacy in HPV‐associated cancers

Ad‐E6/7‐HR vaccine improves the prophylactic and therapeutic efficacy in HPV‐associated cancers

Abstract Background High‐risk human papillomavirus (HPV), especially HPV16, is closely correlated with certain cancers. E6 and E7 proteins of HPV16 play critical roles in oncogenesis, making them optimal targets for treating HPV‐associated cancers. Here, we engineered an innovative vaccine, Ad‐E6/7‐...

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Main Authors: Yu Zhang, Ke Qiu, Jiayuan Ai, Maosen Xu, Binhan Wang, Aqu Alu, Chunjun Ye, Xiya Huang, Yingqiong Zhou, Zhiruo Song, Jie Shi, Yishan Lu, Yuquan Wei, Jianjun Ren, Yu Zhao, Ping Cheng, Xiawei Wei
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Clinical and Translational Medicine
Subjects:
adenovirus vaccine
cellular immunity
human‐papillomavirus‐associated cancers
oncology
Online Access:https://doi.org/10.1002/ctm2.70305
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https://doi.org/10.1002/ctm2.70305

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