Directing cell delivery to murine atherosclerotic aortic lesions via targeting inflamed circulatory interface using nanocarriers

Directing cell delivery to murine atherosclerotic aortic lesions via targeting inflamed circulatory interface using nanocarriers

Stem cell therapy holds significant potential for many inflammatory diseases and regenerative medicine applications. However, delivery of therapeutic cells to specific disease sites after systemic administration without indiscriminate trafficking to other non-target tissues is a major limitation of...

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Main Authors: Carlos Theodore Huerta, Leiming Zhang, Yulexi Y. Ortiz, Yan Li, Elnaz Zeynaloo, Emre Dikici, Teruna J. Siahaan, Sapna K. Deo, Sylvia Daunert, Zhao-Jun Liu, Omaida C. Velazquez
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
stem cell therapy
cell-based therapy
atherosclerosis
targeted cell delivery
ICAM-1/LFA-1
nanocarriers
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1517320/full
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https://www.frontiersin.org/articles/10.3389/fcvm.2025.1517320/full

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