N-Cadherin based adhesion and Rac1 activity regulate tension polarization in the actin cortex
Abstract Tension-adhesion interplay is a crucial mechanism in multicellular organisms that determines the tension differential among internal and external interfaces, which in turn, mediates tissue surface tension and cell sorting, morphogenesis and remodeling, and cancer progression. Cadherins are...
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Main Authors: | Seyedsajad Moazzeni, Kelly Kyker-Snowman, Rick I. Cohen, Huan Wang, Ran Li, David I. Shreiber, Jeffrey D. Zahn, Zheng Shi, Hao Lin |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-02-01
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Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-025-88537-9 |
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