Ubiquitin-Specific Protease Inhibitors for Cancer Therapy: Recent Advances and Future Prospects

Ubiquitin-Specific Protease Inhibitors for Cancer Therapy: Recent Advances and Future Prospects

Cancer management has traditionally depended on chemotherapy as the mainstay of treatment; however, recent advancements in targeted therapies and immunotherapies have offered new options. Ubiquitin-specific proteases (USPs) have emerged as promising therapeutic targets in cancer treatment due to the...

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Bibliographic Details
Main Authors: Mohamad Bakkar, Sara Khalil, Komal Bhayekar, Narva Deshwar Kushwaha, Amirreza Samarbakhsh, Sadaf Dorandish, Holly Edwards, Q. Ping Dou, Yubin Ge, Navnath S. Gavande
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Biomolecules
Subjects:
ubiquitin-specific proteases (USPs)
deubiquitinating enzymes (DUBs)
small molecule inhibitors
cancer therapy
Online Access:https://www.mdpi.com/2218-273X/15/2/240
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