Development and validation of a Guinea pig model for concurrent allergic rhinitis and asthma using recombinant Der f 2

Development and validation of a Guinea pig model for concurrent allergic rhinitis and asthma using recombinant Der f 2

Abstract Background This study aimed to develop a guinea pig model of concurrent allergic rhinitis and asthma. Methods Thirty-three guinea pigs were randomly divided into the control group and the experimental group. Guinea pigs in the experimental group were sensitized by intraperitoneal injection...

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Bibliographic Details
Main Authors: Feng Xu, Li Hu, Jianzhong Wang, Lineng Zhang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Pulmonary Medicine
Subjects:
Allergic rhinitis
Asthma
Guinea pig
Intraperitoneal administration
Inhalation
Der f 2
Online Access:https://doi.org/10.1186/s12890-025-03534-y
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https://doi.org/10.1186/s12890-025-03534-y

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