Subtype-specific role for Jagged1 in promoting or inhibiting breast tumor formation
Abstract Notch signaling is altered in breast cancer. Recent studies highlighted both tumor-suppressive and oncogenic roles for Notch in this tissue. The function of Jagged1, the most highly expressed Notch ligand in the mammary gland, is not well defined. Here we report that deletion of Jagged1 in...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-01-01
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| Series: | Oncogenesis |
| Online Access: | https://doi.org/10.1038/s41389-025-00545-6 |
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