Loneliness and biomarkers of brain pathology in people with subjective cognitive decline

Loneliness and biomarkers of brain pathology in people with subjective cognitive decline

Abstract Loneliness is a neuropsychiatric symptom that has been associated with cognitive impairment and dementia. We aimed to investigate whether depressive symptomatology and biomarkers of Alzheimer’s disease (AD) and cerebrovascular disease (CVD) are associated with loneliness. Secondly, we aimed...

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Main Authors: Mariola Zapater-Fajarí, Isabel Crespo-Sanmiguel, Nira Cedres, Therese Rydberg Sterner, Lina Rydén, Simona Sacuiu, Margda Waern, Anna Zettergren, Henrik Zetterberg, Kaj Blennow, Silke Kern, Vanesa Hidalgo, Alicia Salvador, Eric Westman, Ingmar Skoog, Daniel Ferreira
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Lonely
Depressive symptomatology
Alzheimer’s disease biomarkers
Cerebrovascular disease
Subjective cognitive impairment
Online Access:https://doi.org/10.1038/s41598-025-95411-1
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https://doi.org/10.1038/s41598-025-95411-1

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