Effects of different types of ginseng on intercellular wireless communication networks and central carbon metabolism pathways
Ginseng has high medicinal value. Different ginseng have different benefits, but how they work in the body's immune metabolism is unclear. In this study, different types of ginseng were ingested and serum cytokines, some metabolite concentrations and metabolic enzyme expression levels were meas...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co. Ltd.
2025-11-01
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| Series: | Journal of Future Foods |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772566924000922 |
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| _version_ | 1832582112569458688 |
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| author | Yujiao Liu Dingqiang Lu Jiayi Qiang Lianjie Xu Ming Li Xinqian Wang Yixuan Liu Yifei Zhang Wei Xu Chenyu Xu Qingwei Song Wenling Wu Yimeng Bi Ruijuan Ren Guangchang Pang |
| author_facet | Yujiao Liu Dingqiang Lu Jiayi Qiang Lianjie Xu Ming Li Xinqian Wang Yixuan Liu Yifei Zhang Wei Xu Chenyu Xu Qingwei Song Wenling Wu Yimeng Bi Ruijuan Ren Guangchang Pang |
| author_sort | Yujiao Liu |
| collection | DOAJ |
| description | Ginseng has high medicinal value. Different ginseng have different benefits, but how they work in the body's immune metabolism is unclear. In this study, different types of ginseng were ingested and serum cytokines, some metabolite concentrations and metabolic enzyme expression levels were measured. Intercellular communication networks and metabolic networks were constructed and analyzed for correlation. The results show that the effect of wild ginseng on cytokine secretion and metabolic pathway fluxes was greater. An intake of garden ginseng activated aerobic glycolysis to enhance immunity, while an intake of forest ginseng and wild ginseng increased pentose phosphate pathway, tricarboxylic acid cycle, and oxidative phosphorylation activity to promote immunity. Therefore, the intake of 500 mg/person of forest ginseng or 100 mg/person of wild ginseng was beneficial to health. The study of cytokines and metabolic networks may also provide new ideas for exploring the effects of ginseng and others on the body. |
| format | Article |
| id | doaj-art-a2fe45eb1c844e8ca3d4d3167bcfa466 |
| institution | Kabale University |
| issn | 2772-5669 |
| language | English |
| publishDate | 2025-11-01 |
| publisher | KeAi Communications Co. Ltd. |
| record_format | Article |
| series | Journal of Future Foods |
| spelling | doaj-art-a2fe45eb1c844e8ca3d4d3167bcfa4662025-01-30T05:15:14ZengKeAi Communications Co. Ltd.Journal of Future Foods2772-56692025-11-0156572581Effects of different types of ginseng on intercellular wireless communication networks and central carbon metabolism pathwaysYujiao Liu0Dingqiang Lu1Jiayi Qiang2Lianjie Xu3Ming Li4Xinqian Wang5Yixuan Liu6Yifei Zhang7Wei Xu8Chenyu Xu9Qingwei Song10Wenling Wu11Yimeng Bi12Ruijuan Ren13Guangchang Pang14Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, ChinaTianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, China; Corresponding authors.Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, ChinaTianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, ChinaTianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, ChinaTianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, ChinaTianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, ChinaTianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, ChinaTianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, ChinaTianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, ChinaTianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, ChinaTianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, ChinaTianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, ChinaTianjin Institute for Food Safety Inspection Technology, Tianjin 300134, China; Corresponding authors.Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300314, China; Corresponding authors.Ginseng has high medicinal value. Different ginseng have different benefits, but how they work in the body's immune metabolism is unclear. In this study, different types of ginseng were ingested and serum cytokines, some metabolite concentrations and metabolic enzyme expression levels were measured. Intercellular communication networks and metabolic networks were constructed and analyzed for correlation. The results show that the effect of wild ginseng on cytokine secretion and metabolic pathway fluxes was greater. An intake of garden ginseng activated aerobic glycolysis to enhance immunity, while an intake of forest ginseng and wild ginseng increased pentose phosphate pathway, tricarboxylic acid cycle, and oxidative phosphorylation activity to promote immunity. Therefore, the intake of 500 mg/person of forest ginseng or 100 mg/person of wild ginseng was beneficial to health. The study of cytokines and metabolic networks may also provide new ideas for exploring the effects of ginseng and others on the body.http://www.sciencedirect.com/science/article/pii/S2772566924000922GinsengCytokinesMetabolic pathwaysMetabolic enzymesIntercellular wireless communication networkCentral carbon metabolism network |
| spellingShingle | Yujiao Liu Dingqiang Lu Jiayi Qiang Lianjie Xu Ming Li Xinqian Wang Yixuan Liu Yifei Zhang Wei Xu Chenyu Xu Qingwei Song Wenling Wu Yimeng Bi Ruijuan Ren Guangchang Pang Effects of different types of ginseng on intercellular wireless communication networks and central carbon metabolism pathways Journal of Future Foods Ginseng Cytokines Metabolic pathways Metabolic enzymes Intercellular wireless communication network Central carbon metabolism network |
| title | Effects of different types of ginseng on intercellular wireless communication networks and central carbon metabolism pathways |
| title_full | Effects of different types of ginseng on intercellular wireless communication networks and central carbon metabolism pathways |
| title_fullStr | Effects of different types of ginseng on intercellular wireless communication networks and central carbon metabolism pathways |
| title_full_unstemmed | Effects of different types of ginseng on intercellular wireless communication networks and central carbon metabolism pathways |
| title_short | Effects of different types of ginseng on intercellular wireless communication networks and central carbon metabolism pathways |
| title_sort | effects of different types of ginseng on intercellular wireless communication networks and central carbon metabolism pathways |
| topic | Ginseng Cytokines Metabolic pathways Metabolic enzymes Intercellular wireless communication network Central carbon metabolism network |
| url | http://www.sciencedirect.com/science/article/pii/S2772566924000922 |
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