Impregnation of mesenchymal stem cell conditioned media with wortmannin enhanced its antiproliferative effect in breast cancer cells via PI3K/Akt/mTOR pathway

Abstract Background/aim Conditioned media derived from Mesenchymal stem cells (MSC-CM) was suggested as a promising alternative cell-free regenerative therapy. It is hypothesized that the synergistic effect of MSC-CM with anticancer drugs may improve their antiproliferative and antimetastatic effect...

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Bibliographic Details
Main Authors: Doha F. Ismail, Mai M. El-Keey, Saad M. Elgendy, Mohamed Hessien
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Research Notes
Subjects:
Online Access:https://doi.org/10.1186/s13104-025-07124-3
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