Carboxylated Mesoporous Carbon Nanoparticles as Bicalutamide Carriers with Improved Biopharmaceutical and Chemo-Photothermal Characteristics

Carboxylated Mesoporous Carbon Nanoparticles as Bicalutamide Carriers with Improved Biopharmaceutical and Chemo-Photothermal Characteristics

Prostate cancer is a serious, life-threatening condition among men, usually requiring long-term chemotherapy. Due to its high efficacy, bicalutamide, a non-steroidal anti-androgen, has widespread use. However, its poor water solubility, low oral bioavailability, and nonspecific systemic exposure lim...

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Bibliographic Details
Main Authors: Teodora Popova, Borislav Tzankov, Marta Slavkova, Yordan Yordanov, Denitsa Stefanova, Virginia Tzankova, Diana Tzankova, Ivanka Spassova, Daniela Kovacheva, Christina Voycheva
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Molecules
Subjects:
mesoporous carbon nanoparticles
drug delivery
functionalization
bicalutamide
encapsulation
prostate cancer
Online Access:https://www.mdpi.com/1420-3049/30/15/3055
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